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Alex J Shortt: Consultant Eye Surgeon and Clinical Academic Ophthalmologist, Harley Street, London

Mr Alex Shortt HSG
Alex J Shortt: Consultant Eye Surgeon & Clinical Academic Ophthalmologist, Harley Street, London
 A leading Harley Street-based Consultant Ophthalmic Surgeon and clinician-scientist with a specialist expertise in corneal and external eye disease, cataract surgery and laser eye surgery.

Mr Alex J Shortt, MB BCh, MSc, PhD, FRCOphth, is a Wellcome Trust Fellow and Clinician-Scientist at UCL Institute of Ophthalmology and UCL Institute of Immunity and Transplantation, and Honorary Consultant Ophthalmologist, Cornea and External Eye Disease at Moorfields Eye Hospital in London.

Based at Optegra Eye Hospital London in the heart of London's medical district, Mr Shortt provides the most up-to-date treatments for corneal eye disease and ocular surface problems, including stem cell transplantation, as well as the full range of laser treatments and implantable intraocular lenses (IOLs) for cataracts and refractive eye problems.

About Alex J Shortt

Mr Alex Shortt - Harley Street office

Mr Shortt graduated top of his class from University College Dublin Medical School in 1999 and went on to complete his postgraduate training in Ophthalmology at Moorfields Eye Hospital in London, where he was awarded the Crombie and Harcourt medals for performance in the MRCOphth examinations.

Following the completion of his PhD thesis at University College London (UCL) in 2009, Mr Shortt undertook an NIHR Clinical Lectureship at the NIHR Biomedical Research Centre at Moorfields and the UCL Institute of Ophthalmology, followed by fellowships in corneal and conjunctival disease at Moorfields. Since 2014, he has held the post of Wellcome Trust Fellow and Clinical Scientist at UCL Institute of Ophthalmology and UCL Institute of Immunity and Transplantation, and Honorary Consultant Ophthalmologist specialising in cornea and external eye disease at Moorfields Eye Hospital, London.

Mr Shortt is the Editor of the Cornea Section for Eye, The Journal of the Royal College of Ophthalmologists and sits on the editorial board for various other academic journals. Over the years his work has been recognised by numerous awards and distinctions, including the Oxford Ophthalmological Congress Founder's Cup, the Moorfield's Research Medal, the Dermot Pierce Prize for Research from the Royal Society of Medicine, and most recently, the Fight for Sight prize.


Mr Alex Shortt - laser eye surgery

Having undertaken joint academic and clinical training at UCL through the NIHR's Integrated Academic Training programme, Mr Shortt combines the roles of clinician-scientist, medical doctor and experienced eye surgeon and has, to date, performed over 150 corneal transplants and 1,000 cataract surgeries. 

Working at the cutting edge of research into corneal and conjunctival disease, Mr Shortt is experienced in the very latest treatments and therapies for these conditions, including stem cell transplantation. His NHS work is focused on the treatment of patients with complex eye diseases of the cornea and he performs stem cell transplants in cases requiring reconstruction of the eye

Research: novel therapies for diseases of the cornea and conjunctiva

Mr Shortt’s primary area of research over the last decade has been on the development of cell therapies for diseases of the cornea and conjunctiva. In 2014 he commenced a prestigious four year Wellcome Trust Clinician Scientist Award investigating the immune response to engrafted stem cells and his ultimate goal is to improve the lives of patients with chronic, severe ocular surface disease through the delivery of novel cellular therapies using different therapeutic cell types. 

Mr Shortt's current research activities and interests are:

  • Corneal transplant biology and immunology
  • Corneal stem cell biology and immunology
  • Clinical trials of novel corneal therapies
  • Translation of novel corneal therapies into clinical practice
  • Clinical outcomes of limbal stem cell transplantation
  • Tracking of stem cells post transplantation using quantum dot technology
  • Complex corneal and ocular surface disorders
  • Novel approaches to ocular surface reconstruction
  • 3D imaging of the corneal limbal niche
  • In-vivo imaging of limbal epithelial stem cells
  • Optimisation of clinical limbal stem cell cultures
  • Structural and functional aspects of the limbal niche
  • Systematic review and meta-analysis

Private ophthalmic treatment

Mr Alex Shortt - Harley Street door
Based at Optegra Eye Hospital London, Mr Shortt provides private treatment for cataracts (including complex cases such as those associated with ocular surface disease and glaucoma), refractive errors (short-sightedness, long-sightedness, astigmatism and presbyopia), external eye problems (dry eye, Sjogren's syndrome and blepharitis) and corneal disease (keratoconus and Fuch's endothelial dystrophy).


Mr Short welcomes both self-paying and insured patients and is fee assured with all the major insurers, including BUPA, AXA PPP and Aviva. His fees are as follows:

Initial consultation: £250
Follow-up consultation: £175
Pentacam corneal scan: £150
OCT Corneal Scan: £150

GMC registration details 

GMC number:


Check this doctor’s GMC registration

Date of registration:

19 Mar 2003



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Visit Harley Street


  • Corneal disease (keratoconus, Fuch's Endothelial dystrophy)
  • Laser vision correction / Laser eye surgery
  • Laser cataract surgery
  • Ocular surface reconstruction
  • Stem cell transplantation
  • Academic corneal research



  • MB BCh
  • MSc
  • PhD
  • FRCOphth
  • PGDipCRS


  • Fellow of The Royal College of Ophthalmologists
  • President elect of MCLOSA – The British Ocular Surface Society
  • Member of the United Kingdom & Ireland Society of Refractive and Cataract Surgery
  • Member of the Association for Research in Vision and Ophthalmology (ARVO)
  • Member of the European Society of Cataract and Refractive Surgery


Private Practice

    • Advanced Vision Care
  • Optegra Eye Hospital London

NHS Practice

  • UCL Institute of Immunity and Transplantation



Mr Alex J Shortt

Optegra Eye Hospital London
77 Harley Street

Tel: +44 (0) 20 3808 7758

Email: adminteam@alexshortt.co.uk

Website: www.alexshortt.co.uk